Premenstrual dysphoric disorder (PMDD) A severe form of premenstrual syndrome (PMS) that causes depression and anxiety during the luteal phase of the menstrual cycle (after ovulation). Related Articles: Premenstrual Dysphoric Disorder & the Language of DiagnosisHave you heard of Premenstrual Dysphoric Disorder? Not likely. Sasha Co- Founder of Psych n Sex, previous writer and campus educator for the Kinsey Institute & published psychology researcher. Manhattan girl obsessed with post ww2 abstract expressionism, beet juice, vintage clothing & Scandinavia.